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This genetic condition affects the optic nerve, and cyanocobalamin can accelerate optic atrophy in affected individuals
Salama RM, Mohamed AM, Hamed NS, Ata RM, NourelDeen AS, Hassan MA (2020) Alogliptin: a novel approach against cyclophosphamide-induced hepatic injury via modulating SIRT1/FoxO1 pathway
This is enzyme inhibition, not a permanent change: once the compound clears, NNMT starts methylating nicotinamide again and the metabolic tilt goes with it
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